Release 3.0
last update on 10 Dez 2009
This Internet database integrates information on sequence and structure of lipases and related proteins sharing the same a/b hydrolase fold to facilitate protein engineering. We acknowledge your comments or contribution to this page: please send us information to be included in this database.
Browse database by classification

a/b hydrolase fold families

GGGX class   GX class   Y class

Browse database by organism

Organism
Browse database by structures

Structures
Perform homology search against the lipase database

BLAST search
Query the Lipase Engineering Database using SQL

SQL query
Download database content

Database content
readme.txt
Links to related websites

Links
This database is maintained by Jürgen Pleiss. Institute of Technical Biochemistry, University of Stuttgart, Allmandring 31, 70569 Stuttgart, Germany

Publications:

M.Widmann, P.B.Juhl, J.Pleiss 2010. Structural classification by the Lipase Engineering Database: a case study of Candida antarctica lipase A. BMC Genomics 11: 123

M.Fischer, Q.K.Thai, M.Grieb, J.Pleiss 2006. DWARF - a data warehouse system for analyzing protein families. BMC Bioinformatics 7: 495-495

S. Barth, M. Fischer, R. D. Schmid, J. Pleiss, "The database of epoxide hydrolases and haloalkane dehalogenases: one structure, many functions." , Bioinformatics (2004) 20 (16), 2845-2847

S. Barth, M. Fischer, R. D. Schmid, J. Pleiss, "Sequence and structure of epoxide hydrolases: a systematic analysis" , Proteins: Structure, Function, and Genetics (2004) 55, 846-855

M. Fischer, J. Pleiss, "The Lipase Engineering Database: a navigation and analysis tool for protein families", Nucl. Acid. Res. (2003) 31, 319-321

J. Pleiss, M. Fischer, M. Peiker, C. Thiele, R. D. Schmid, "Lipase Engineering Database: Understanding and exploiting sequence-structure-function relationships", J. Mol. Catal. B: Enzym. (2000) 10, 491-508

This database system was developed by Markus Fischer. We acknowledge valuable contributions by Sandra Barth, Claudia Schmidt-Dannert, Dang Sy Hai, Melanie Grieb, Christoph Kaiser, Michael Knoll, Thomas Kosian, Marcus Peiker, Darius Schwenger, Alexander Steudle, Marco Strohmeier, Claudia Thiele, Sadhna Tyagi, Thai Ke Quan, Florian Wagner, Michael Widmann, Peter Benjamin Juhl and Xiaolei Yu.